https://wiki.tiffa.net/w/index.php?action=history&feed=atom&title=Translations%3AEnzyme%2F74%2FenTranslations:Enzyme/74/en - Revision history2026-10-09T13:45:49ZRevision history for this page on the wikiMediaWiki 1.43.0https://wiki.tiffa.net/w/index.php?title=Translations:Enzyme/74/en&diff=118912&oldid=prevFuzzyBot: Importing a new version from external source2024-02-21T10:18:19Z<p>Importing a new version from external source</p>
<p><b>New page</b></p><div>====Competitive====<br />
A [[competitive inhibitor]] and substrate cannot bind to the enzyme at the same time. Often competitive inhibitors strongly resemble the real substrate of the enzyme. For example, the drug [[methotrexate]] is a competitive inhibitor of the enzyme [[dihydrofolate reductase]], which catalyzes the reduction of [[folic acid|dihydrofolate]] to tetrahydrofolate. The similarity between the structures of dihydrofolate and this drug are shown in the accompanying figure. This type of inhibition can be overcome with high substrate concentration. In some cases, the inhibitor can bind to a site other than the binding-site of the usual substrate and exert an [[#Allosteric modulation|allosteric effect]] to change the shape of the usual binding-site.</div>FuzzyBot