https://wiki.tiffa.net/w/index.php?action=history&feed=atom&title=Translations%3ADyslipidemia%2F7%2Fen 2026-08-15T06:17:55Z Revision history for this page on the wiki MediaWiki 1.43.0 https://wiki.tiffa.net/w/index.php?title=Translations:Dyslipidemia/7/en&diff=138767&oldid=prev 2024-04-13T08:52:05Z

<p>Importing a new version from external source</p> <p><b>New page</b></p><div>Dyslipidemias can also be classified based on the underlying cause, whether it is primary, secondary, or a combination of both. Primary dyslipidemias are caused by [[genetic disorder]]s that can cause abnormal lipid levels without any other obvious risk factors. Those with primary dyslipidemias are at higher risk of getting complications of dyslipidemias, such as [[Cardiovascular disease|atherosclerotic cardiovascular disease]], at a younger age. Some common genetic disorders associated with primary dyslipidemias are [[Familial hypercholesterolemia|homozygous or heterozygous hypercholesterolemia]], [[familial hypertriglyceridemia]], [[combined hyperlipidemia]], and HDL-C metabolism disorders. In familial hypercholesterolemia, a mutation in the &#039;&#039;LDLR&#039;&#039;, &#039;&#039;PCSK9&#039;&#039;, or &#039;&#039;APOB&#039;&#039; is usually the reason for this and these mutations result in high LDL cholesterol. In combined hyperlipidemia, there is an overproduction of apoB-100 in the liver. This causes high amounts of LDL and VLDL molecules to form. A unique sign of primary dyslipidemias is that patients will often present with acute pancreatitis or [[xanthoma]]s on the skin, eyelids or around the cornea. In contrast to primary dyslipidemias, secondary dyslipidemas are based on modifiable environmental or lifestyle factors. Some diseases that are associated with a higher risk of dyslipidemia are uncontrolled [[Diabetes|diabetes mellitus]], cholestatic liver disease, [[chronic kidney disease]], [[hypothyroidism]], and [[Polycystic ovary syndrome|polycystic ovarian syndrome]]. What people eat can also have an influence, with excessive alcohol use, too much carbohydrates, and diets high in saturated fats having a higher risk. Some medications that may contribute to dyslipidemia are [[Thiazide|thiazide diuretics]], [[beta blocker]]s, [[Oral contraceptive pill|oral contraceptives]], [[atypical antipsychotic]]s (clozapine, olanzapine), [[corticosteroid]]s, [[tacrolimus]], and [[Ciclosporin|cyclosporine]]. Other non-hereditary factors that increase the risk of dyslipidemias are smoking, pregnancy, and obesity.</div>

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