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The three main blood levels collected to assess for dyslipidemia is [[triglyceride]]s (TG), [[High-density lipoprotein|high density lipoprotein]] cholesterol (HDL-C), and [[Low-density lipoprotein|low density lipoprotein]] cholesterol (LDL-C). [[Hypertriglyceridemia|High triglyceride]] levels (>1.7 mmol/L fasting) can indicate dyslipidemia. Triglycerides are transported through the blood by using [[Very low-density lipoprotein|very low density lipoproteins]] (VLDL) as a carrier. One thing to note when measuring triglyceride levels is that [[fasting]] for 8–12 hours is required to get an accurate result as non-fasting TG results may be falsely elevated. If TG results are greater than 10 mmol/L, then this needs to be addressed since severe hypertriglceridemia is a risk factor for acute [[Acute pancreatitis|pancreatitis]]. Another blood level collected to assess dyslipidemia is HDL-C. HDL cholesterol is made up of very little lipids and a high amount of protein. It is beneficial in the body because it functions by going to the tissues and picking up extra [[cholesterol]] and [[fat]]. Due to the positive effects of HDL-C, it is named "good cholesterol" since it helps prevent plaque formation. Other functions of HDL-C is promoting cardiovascular health such as antioxidation effects, protection against [[thrombosis]], maintenance of endothelial function, and maintaining low blood viscosity. Due to the positive functions of HDL cholesterol, a low level indicates dyslipidemia and is a risk factor for complications. Another diagnostic test that is often reviewed is LDL cholesterol. Low density lipoproteins are made up of cholesterol, TG, phospholipids, and [[apolipoprotein]]s. LDL-C molecules bind to the endothelium of blood vessels and cause plaque formation. Once plaques are formed, LDL-C floating in the bloodstream can attach to the plaques and cause further accumulation. In addition to plaque formation, LDL-C molecules can undergo oxidation. Oxidation can cause further accumulation of cholesterol and the release of [[inflammatory cytokine]]s, which damages the blood vessels. Due to the damaging effects of LDL-C, high levels increase the risk for cardiovascular disease and indicate dyslipidemia.

Translations:Dyslipidemia/6/en - Revision history

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