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===Type 1===
{{Main|Type 1 diabetes}}
Type 1 accounts for 5 to 10% of diabetes cases and is the most common type diagnosed in patients under 20 years; however, the older term "juvenile-onset diabetes" is no longer used as the disease not uncommonly has onset in adulthood. The disease is characterized by loss of the insulin-producing [[beta cell]]s of the [[pancreatic islets]], leading to severe insulin deficiency, and can be further classified as [[immune-mediated]] or [[Idiopathic disease|idiopathic]] (without known cause). The majority of cases are immune-mediated, in which a [[T cell]]-mediated [[autoimmunity|autoimmune]] attack causes loss of beta cells and thus insulin deficiency. Patients often have irregular and unpredictable blood sugar levels due to very low insulin and an impaired counter-response to hypoglycaemia.
[[File:Type 1 Diabetes Mellitus.jpg|thumb|Autoimmune attack in type 1 diabetes.]]
Type 1 diabetes is partly [[Genetic disorder|inherited]], with multiple genes, including certain [[Human leukocyte antigen|HLA genotypes]], known to influence the risk of diabetes. In genetically susceptible people, the onset of diabetes can be triggered by one or more [[environmental factor]]s, such as a [[viral infection]] or diet. Several viruses have been implicated, but to date there is no stringent evidence to support this hypothesis in humans.

Translations:Diabetes/15/en - Revision history

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