https://wiki.tiffa.net/w/index.php?action=history&feed=atom&title=Translations%3ACytochrome_P450%2F4%2Fen 2026-11-02T15:01:10Z Revision history for this page on the wiki MediaWiki 1.43.0 https://wiki.tiffa.net/w/index.php?title=Translations:Cytochrome_P450/4/en&diff=129029&oldid=prev 2024-03-15T11:35:28Z

<p>Importing a new version from external source</p> <p><b>New page</b></p><div>==Nomenclature==<br /> [[Gene]]s encoding P450 enzymes, and the enzymes themselves, are designated with the [[gene nomenclature#Symbol and name|root symbol]] &#039;&#039;&#039;CYP&#039;&#039;&#039; for the [[protein superfamily|superfamily]], followed by a number indicating the [[gene family]], a capital letter indicating the subfamily, and another numeral for the individual gene. The convention is to &#039;&#039;[[Italic type|italicise]]&#039;&#039; the name when referring to the gene. For example, &#039;&#039;CYP2E1&#039;&#039; is the gene that encodes the enzyme [[CYP2E1]]—one of the enzymes involved in [[paracetamol]] (acetaminophen) metabolism. The &#039;&#039;&#039;CYP&#039;&#039;&#039; nomenclature is the official naming convention, although occasionally &#039;&#039;&#039;CYP450&#039;&#039;&#039; or &#039;&#039;&#039;CYP&lt;sub&gt;450&lt;/sub&gt;&#039;&#039;&#039; is used synonymously. These names should never be used as according to the nomenclature convention (as they denote a P450 in family number 450). However, some gene or enzyme names for P450s are also referred to by historical names (e.g. P450&lt;sub&gt;BM3&lt;/sub&gt; for CYP102A1) or functional names, denoting the catalytic activity and the name of the compound used as substrate. Examples include [[CYP5A1]], [[thromboxane]] A&lt;sub&gt;2&lt;/sub&gt; synthase, abbreviated to [[Thromboxane-A synthase|TBXAS1]] (&#039;&#039;&#039;T&#039;&#039;&#039;hrom&#039;&#039;&#039;B&#039;&#039;&#039;o&#039;&#039;&#039;X&#039;&#039;&#039;ane &#039;&#039;&#039;A&#039;&#039;&#039;&lt;sub&gt;2&lt;/sub&gt; &#039;&#039;&#039;S&#039;&#039;&#039;ynthase &#039;&#039;&#039;1&#039;&#039;&#039;), and [[CYP51A1]], lanosterol 14-α-demethylase, sometimes unofficially abbreviated to LDM according to its substrate (&#039;&#039;&#039;L&#039;&#039;&#039;anosterol) and activity (&#039;&#039;&#039;D&#039;&#039;&#039;e&#039;&#039;&#039;M&#039;&#039;&#039;ethylation).</div>

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