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	<title>Translations:Common cold/15/en - Revision history</title>
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		<title>FuzzyBot: Importing a new version from external source</title>
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&lt;p&gt;&lt;b&gt;New page&lt;/b&gt;&lt;/p&gt;&lt;div&gt;==Pathophysiology==&lt;br /&gt;
[[File:Illu conducting passages.svg|thumb|upright|The common cold is a disease of the [[upper respiratory tract]].]]&lt;br /&gt;
The symptoms of the common cold are believed to be primarily related to the [[immune]] response to the virus. The mechanism of this immune response is virus-specific. For example, the rhinovirus is typically acquired by direct contact; it binds to humans via [[ICAM-1|ICAM-1 receptors]] and the [[Cadherin related family member 3|CDHR3 receptor]] through unknown mechanisms to trigger the release of [[inflammatory mediators]]. These inflammatory mediators then produce the symptoms. It does not generally cause damage to the nasal [[epithelium]]. The respiratory syncytial virus ([[Human respiratory syncytial virus|RSV]]), on the other hand, is contracted by direct contact and airborne droplets. It then replicates in the nose and throat before frequently spreading to the [[lower respiratory tract]]. RSV does cause epithelium damage. Human [[parainfluenza]] virus typically results in inflammation of the nose, throat, and [[bronchus|bronchi]]. In young children, when it affects the [[Vertebrate trachea|trachea]], it may produce the symptoms of [[croup]], due to the small size of their airways.&lt;/div&gt;</summary>
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