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	<title>Translations:Citric acid cycle/36/en - Revision history</title>
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	<updated>2026-09-14T09:29:11Z</updated>
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		<title>FuzzyBot: Importing a new version from external source</title>
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		<updated>2024-03-31T02:38:40Z</updated>

		<summary type="html">&lt;p&gt;Importing a new version from external source&lt;/p&gt;
&lt;p&gt;&lt;b&gt;New page&lt;/b&gt;&lt;/p&gt;&lt;div&gt;In the liver, the carboxylation of [[cytosol]]ic pyruvate into intra-mitochondrial &amp;#039;&amp;#039;oxaloacetate&amp;#039;&amp;#039; is an early step in the [[gluconeogenesis|gluconeogenic]] pathway which converts [[lactic acid|lactate]] and de-aminated [[alanine]] into glucose, under the influence of high levels of [[glucagon]] and/or [[epinephrine]] in the blood. Here the addition of &amp;#039;&amp;#039;oxaloacetate&amp;#039;&amp;#039; to the mitochondrion does not have a net anaplerotic effect, as another citric acid cycle intermediate (&amp;#039;&amp;#039;malate&amp;#039;&amp;#039;) is immediately removed from the mitochondrion to be converted into cytosolic oxaloacetate, which is ultimately converted into glucose, in a process that is almost the reverse of [[glycolysis]].&lt;/div&gt;</summary>
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