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	<title>Translations:Citric acid cycle/28/en - Revision history</title>
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	<updated>2026-09-14T09:30:45Z</updated>
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		<title>FuzzyBot: Importing a new version from external source</title>
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		<updated>2024-03-31T02:38:40Z</updated>

		<summary type="html">&lt;p&gt;Importing a new version from external source&lt;/p&gt;
&lt;p&gt;&lt;b&gt;New page&lt;/b&gt;&lt;/p&gt;&lt;div&gt;&amp;#039;&amp;#039;&amp;#039;Regulation by calcium&amp;#039;&amp;#039;&amp;#039;. Calcium is also used as a regulator in the citric acid cycle. Calcium levels in the mitochondrial matrix can reach up to the tens of micromolar levels during cellular activation. It activates [[pyruvate dehydrogenase phosphatase]] which in turn activates the [[pyruvate dehydrogenase complex]]. Calcium also activates [[isocitrate dehydrogenase]] and [[Alpha-ketoglutarate dehydrogenase|α-ketoglutarate dehydrogenase]]. This increases the reaction rate of many of the steps in the cycle, and therefore increases flux throughout the pathway.&lt;/div&gt;</summary>
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