https://wiki.tiffa.net/w/index.php?action=history&feed=atom&title=Translations%3ACitric_acid_cycle%2F23%2FenTranslations:Citric acid cycle/23/en - Revision history2026-09-14T08:58:32ZRevision history for this page on the wikiMediaWiki 1.43.0https://wiki.tiffa.net/w/index.php?title=Translations:Citric_acid_cycle/23/en&diff=132122&oldid=prevFuzzyBot: Importing a new version from external source2024-03-31T02:38:40Z<p>Importing a new version from external source</p>
<p><b>New page</b></p><div>A step with significant variability is the conversion of succinyl-CoA to succinate. Most organisms utilize [http://www.enzyme-database.org/query.php?ec=6.2.1.5 EC 6.2.1.5], succinate–CoA ligase (ADP-forming) (despite its name, the enzyme operates in the pathway in the direction of ATP formation). In mammals a GTP-forming enzyme, succinate–CoA ligase (GDP-forming) ([http://www.enzyme-database.org/query.php?ec=6.2.1.4 EC 6.2.1.4]) also operates. The level of utilization of each isoform is tissue dependent. In some acetate-producing bacteria, such as ''Acetobacter aceti'', an entirely different enzyme catalyzes this conversion&nbsp;– [http://www.enzyme-database.org/query.php?ec=2.8.3.18 EC 2.8.3.18], succinyl-CoA:acetate CoA-transferase. This specialized enzyme links the TCA cycle with acetate metabolism in these organisms. Some bacteria, such as ''Helicobacter pylori'', employ yet another enzyme for this conversion&nbsp;– succinyl-CoA:acetoacetate CoA-transferase ([http://www.enzyme-database.org/query.php?ec=2.8.3.5 EC 2.8.3.5]).</div>FuzzyBot