https://wiki.tiffa.net/w/index.php?action=history&feed=atom&title=Translations%3ACalcitriol%2F18%2FenTranslations:Calcitriol/18/en - Revision history2026-05-12T05:44:33ZRevision history for this page on the wikiMediaWiki 1.43.0https://wiki.tiffa.net/w/index.php?title=Translations:Calcitriol/18/en&diff=138193&oldid=prevFuzzyBot: Importing a new version from external source2024-04-12T12:20:34Z<p>Importing a new version from external source</p>
<p><b>New page</b></p><div>Many of the effects of calcitriol are mediated by its interaction with the [[calcitriol receptor]], also called the vitamin D receptor or VDR. For instance, the unbound inactive form of the calcitriol receptor in intestinal epithelial cells resides in the [[cytoplasm]]. When calcitriol binds to the receptor, the [[Ligand (biochemistry)|ligand]]-receptor complex translocates to the [[cell nucleus]], where it acts as a [[transcription factor]] promoting the expression of a gene encoding a [[Vitamin D-dependent calcium-binding protein|calcium binding protein]]. The levels of the calcium binding protein increase enabling the cells to actively transport more calcium ({{chem|Ca|2+}}) from the intestine across the [[intestinal mucosa]] into the blood. Alternative, ''non-genomic'' pathways may be mediated through either [[PDIA3]] or VDR.</div>FuzzyBot