https://wiki.tiffa.net/w/index.php?action=history&feed=atom&title=Translations%3ACalcipotriol%2F22%2FenTranslations:Calcipotriol/22/en - Revision history2026-05-11T13:41:06ZRevision history for this page on the wikiMediaWiki 1.43.0https://wiki.tiffa.net/w/index.php?title=Translations:Calcipotriol/22/en&diff=138450&oldid=prevFuzzyBot: Importing a new version from external source2024-04-12T13:40:44Z<p>Importing a new version from external source</p>
<p><b>New page</b></p><div>The precise mechanism of calcipotriol in remitting psoriasis is not well understood. However, it has been shown to have comparable affinity with calcitriol for the [[vitamin D receptor]] (VDR), while being less than 1% as active as the calcitriol in regulating [[calcium metabolism]]. The vitamin D receptor belongs to the steroid/thyroid receptor superfamily, and is found on the cells of many different tissues including the thyroid, bone, kidney, and [[T cell]]s of the immune system. T cells are known to play a role in psoriasis, and it is thought that the binding of calcipotriol to the VDR modulates the T cells gene transcription of cell differentiation and proliferation related genes.</div>FuzzyBot