https://wiki.tiffa.net/w/index.php?action=history&feed=atom&title=Translations%3AAtherosclerosis%2F70%2FenTranslations:Atherosclerosis/70/en - Revision history2026-09-08T16:32:32ZRevision history for this page on the wikiMediaWiki 1.43.0https://wiki.tiffa.net/w/index.php?title=Translations:Atherosclerosis/70/en&diff=124936&oldid=prevFuzzyBot: Importing a new version from external source2024-03-05T13:10:03Z<p>Importing a new version from external source</p>
<p><b>New page</b></p><div>== Research ==<br />
===Lipids===<br />
An indication of the role of [[high-density lipoprotein]] (HDL) on atherosclerosis has been with the rare [[ApoA-1 Milano|Apo-A1 Milano]] human genetic variant of this [[High-density lipoprotein|HDL]] protein. A small short-term trial using bacterial synthesized human [[ApoA-1 Milano|Apo-A1 Milano]] HDL in people with unstable angina produced a fairly dramatic reduction in measured coronary plaque volume in only six weeks vs. the usual increase in plaque volume in those randomized to placebo. The trial was published in ''[[JAMA]]'' in early 2006. Ongoing work starting in the 1990s may lead to human clinical trials—probably by about 2008. These may use synthesized Apo-A1 Milano HDL directly, or they may use gene-transfer methods to pass the ability to synthesize the Apo-A1 Milano HDLipoprotein.</div>FuzzyBot