https://wiki.tiffa.net/w/index.php?action=history&feed=atom&title=Translations%3AAntihypertensive_drug%2F34%2FenTranslations:Antihypertensive drug/34/en - Revision history2026-11-14T19:24:42ZRevision history for this page on the wikiMediaWiki 1.43.0https://wiki.tiffa.net/w/index.php?title=Translations:Antihypertensive_drug/34/en&diff=72944&oldid=prevFuzzyBot: Importing a new version from external source2023-10-20T03:55:53Z<p>Importing a new version from external source</p>
<p><b>New page</b></p><div>Thiazide diuretics are effective, recommended as the best first-line drug for hypertension, and are much more affordable than other therapies, yet they are not prescribed as often as some newer drugs. [[Chlorthalidone]] is the thiazide drug that is most strongly supported by the evidence as providing a mortality benefit; in the ALLHAT study, a chlorthalidone dose of 12.5&nbsp;mg was used, with titration up to 25&nbsp;mg for those subjects who did not achieve blood pressure control at 12.5&nbsp;mg. Chlorthalidone has repeatedly been found to have a stronger effect on lowering blood pressure than hydrochlorothiazide, and hydrochlorothiazide and chlorthalidone have a similar risk of hypokalemia and other adverse effects at the usual doses prescribed in routine clinical practice. Patients with an exaggerated hypokalemic response to a low dose of a thiazide diuretic should be suspected to have [[hyperaldosteronism]], a common cause of secondary hypertension.</div>FuzzyBot