https://wiki.tiffa.net/w/index.php?action=history&feed=atom&title=Translations%3AAntihypertensive_drug%2F15%2FenTranslations:Antihypertensive drug/15/en - Revision history2026-11-14T20:37:03ZRevision history for this page on the wikiMediaWiki 1.43.0https://wiki.tiffa.net/w/index.php?title=Translations:Antihypertensive_drug/15/en&diff=72925&oldid=prevFuzzyBot: Importing a new version from external source2023-10-20T03:55:52Z<p>Importing a new version from external source</p>
<p><b>New page</b></p><div>As a consequence of AT1 blockade, ARBs increase angiotensin II levels several-fold above baseline by uncoupling a [[negative-feedback]] loop. Increased levels of circulating Angiotensin II result in unopposed stimulation of the AT2 receptors, which are, in addition upregulated. Recent data suggest that AT2 receptor stimulation may be less beneficial than previously proposed and may even be harmful under certain circumstances through mediation of growth promotion, fibrosis, and hypertrophy, as well as proatherogenic and proinflammatory effects.</div>FuzzyBot