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	<title>Translations:Antihypertensive drug/10/en - Revision history</title>
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	<updated>2026-10-10T17:08:28Z</updated>
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		<title>FuzzyBot: Importing a new version from external source</title>
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		<updated>2023-10-20T03:55:52Z</updated>

		<summary type="html">&lt;p&gt;Importing a new version from external source&lt;/p&gt;
&lt;p&gt;&lt;b&gt;New page&lt;/b&gt;&lt;/p&gt;&lt;div&gt;However, ACE inhibitors (and angiotensin II receptor antagonists) should not be a first-line treatment for black hypertensives without [[chronic kidney disease]]. Results from the [[Antihypertensive and Lipid-Lowering Treatment to Prevent Heart Attack Trial|ALLHAT]] trial showed that [[thiazide]]-type diuretics and calcium channel blockers were both more effective as monotherapy in improving cardiovascular outcomes compared to ACE inhibitors for this subgroup. Furthermore, ACE inhibitors were less effective in reducing blood pressure and had a 51% higher risk of stroke in black hypertensives when used as initial therapy compared to a calcium channel blocker. There are fixed-dose [[combination drugs]], such as [[ACE inhibitor and thiazide combination]]s.&lt;/div&gt;</summary>
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