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Translations:Angiotensin II receptor blocker/33/en - Revision history
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<p><b>New page</b></p><div>|-<br />
| [[Valsartan]]<br />
| Diovan<br />
| 6<br />
| 2–4 hrs<br />
| 95%<br />
| 25%<br />
| 30/70%<br />
| Yes<br />
| 80–320<br />
| Substrates: [[Multidrug resistance-associated protein 2|MRP2]] and [[OATP1B1|OATP1B1/SLCO1B1]]<br />
|-<br />
| [[Irbesartan]]<br />
| Avapro<br />
| 11–15<br />
| 1.5–2 hrs<br />
| 90–95%<br />
| 70%<br />
| 20/80%<br />
| No<br />
| 150–300<br />
| Minor substrates of [[CYP2C9]]<br />
|-<br />
| [[Telmisartan]]<br />
| Micardis<br />
| 24<br />
| 0.5–1 hr <br />
| >99%<br />
| 42–58%<br />
| 1/99%<br />
| No<br />
| 40–80<br />
| None known; >97% via biliary excretion<br />
|-<br />
| [[Eprosartan]]<br />
| Teveten<br />
| 5<br />
| 1–2 hrs <br />
| 98%<br />
| 13%<br />
| 30/70%<br />
| No<br />
| 400–800<br />
| None known; >90% via renal and biliary excretion<br />
|-<br />
| [[Olmesartan]]<br />
| Benicar/Olmetec<br />
| 14–16<br />
| 1–2 hrs <br />
| >99%<br />
| 29%<br />
| 40/60%<br />
| No<br />
| 10–40<br />
| Substrates of [[OATP1B1|OATP1B1/SLCO1B1]]<br />
|-<br />
| [[Azilsartan]]<br />
| Edarbi<br />
| 11<br />
| 1.5–3 hrs <br />
| >99%<br />
| 60%<br />
| 55/42%<br />
| No<br />
| 40–80<br />
| Minor substrates of CYP2C9 <br />
|-<br />
| [[Fimasartan]]<br />
| Kanarb<br />
| 7–11<br />
| 0.5–3 hrs after dosing.<br />
| >97%<br />
| 30–40%<br />
| –<br />
| –<br />
| 30–120<br />
| None known; primarily biliary excretion <br />
|-<br />
! Drug<br />
! Trade name<br />
! [[Biological half-life]] [hrs]<br />
! [[Cmax_(pharmacology)|Peak plasma concentration [Tmax] ]]<br />
! [[Protein binding]] [%]<br />
! [[Bioavailability]] [%]<br />
! Renal/hepatic [[Clearance (medicine)|clearance]] [%]<br />
! Food effect<br />
! Daily dosage [mg]<br />
! [[Metabolism]]/[[Transport protein|transporter]]<br />
|}</div>
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