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2024-04-22T10:05:03Z

Created page with "{{Navbox | name = Purine receptor modulators | title = Purine receptor modulators | state = {{{state<includeonly>|collapsed</includeonly>}}} | listclass = hlist | groupstyle = text-align:center; | group1 = Receptor (ligands) | list1 = {{Navbox|child | groupstyle = text-align:center; | groupwidth = 6em; | group1 = P0 (adenine) | list1 = * '''Ag..."

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{{Navbox
| name = Purine receptor modulators
| title = [[Purine receptor]] [[receptor modulator|modulator]]s
| state = {{{state<includeonly>|collapsed</includeonly>}}}
| listclass = hlist
| groupstyle = text-align:center;

| group1 = [[Receptor (biochemistry)|Receptor]] ([[Ligand (biochemistry)|ligand]]s)
| list1 = {{Navbox|child
| groupstyle = text-align:center;
| groupwidth = 6em;

| group1 = [[P0 receptor|P0]] ([[adenine]])
| list1 =
* '''Agonists:''' [[8-Aminoadenine]]
* [[Adenine]]

| group2 = [[Adenosine receptor|P1]] ([[adenosine]])
| list2 =
* '''Agonists:''' [[2-(1-Hexynyl)-N-methyladenosine|2-(1-Hexynyl)-''N''-methyladenosine]]
* [[2-Cl-IB-MECA]]
* [[2'-MeCCPA]]
* [[4'-O-β-D-Glucosyl-9-O-(6'-deoxysaccharosyl)olivil|<nowiki>4'-O-β-D-Glucosyl-9-O-(6''-deoxysaccharosyl)olivil</nowiki>]]
* [[5'-N-ethylcarboxamidoadenosine|5'-''N''-ethylcarboxamidoadenosine]]
* [[Adenosine]]
* [[Adenosine diphosphate|ADP]]
* [[Adenosine monophosphate|AMP]]
* [[Apadenoson]]
* [[ATL-146e]]
* [[Adenosine triphosphate|ATP]]
* [[BAY 60–6583]]
* [[Binodenoson]]
* [[Capadenoson]]
* [[CCPA (biochemistry)|CCPA]]
* [[CGS-21680]]
* [[CP-532,903]]
* [[Evodenoson]]
* [[GR 79236]]
* [[LUF-5835]]
* [[LUF-5845]]
* [[N6-Cyclopentyladenosine|''N''6-Cyclopentyladenosine]]
* [[Namodenoson]]
* [[Neladenoson dalanate]]
* [[Piclidenoson]]
* [[Regadenoson]]
* [[SDZ WAG 994]]
* [[Selodenoson]]
* [[Sonedenoson]]
* [[Tecadenoson]]
* [[UK-432,097]]

* '''Antagonists:''' [[7-Methylxanthine]]
* [[8-Chlorotheophylline]]
* [[8-Phenyl-1,3-dipropylxanthine]]
* [[8-Phenyltheophylline]]
* [[Acefylline]]
* [[Aminophylline]]
* [[ATL-444]]
* [[Bamifylline]]
* [[Cafedrine]]
* [[Caffeine]]
* [[Caffeine citrate]]
* [[Cartazolate]]
* [[CGH-2466]]
* [[CGS-15943]]
* [[Choline theophyllinate]]
* [[Ciforadenant]]
* [[8-Cyclopentyl-1,3-dimethylxanthine|CPX]]
* [[CVT-6883]]
* [[Dimethazan]]
* [[DMPX]]
* [[8-Cyclopentyl-1,3-dipropylxanthine|DPCPX]]
* [[Dyphylline]]
* [[Enprofylline]]
* [[Etazolate]]
* [[Fenethylline]]
* [[IBMX]]
* [[Isovaleric acid]]
* [[Istradefylline]]
* [[KF-26777]]
* [[MRE3008F20]]
* [[MRS-1220]]
* [[MRS-1334]]
* [[MRS-1706]]
* [[MRS-1754]]
* [[MRS-3777]]
* [[Paraxanthine]]
* [[Pentoxifylline]]
* [[Preladenant]]
* [[Propentofylline]]
* [[Proxyphylline]]
* [[PSB-10]]
* [[PSB-11]]
* [[PSB-36]]
* [[PSB-603]]
* [[PSB-788]]
* [[PSB-1115]]
* [[Reversine]]
* [[Rolofylline]]
* [[SCH-442,416]]
* [[SCH-58261]]
* [[Theacrine]]
* [[Theobromine]]
* [[Theodrenaline]]
* [[Theophylline]]
* [[Tozadenant]]
* [[Tracazolate]]
* [[VUF-5574]]
* [[ZM-241,385]]

| group3 = [[P2 receptor|P2]] ([[nucleotide]])
| list3 = {{Navbox|child
| groupstyle = text-align:center;
| groupwidth = 3em;

| group1 = [[P2X purinoreceptor|P2X]] ({{abbrlink|ATP|Adenosine triphosphate}})
| list1 =
* '''Agonists:''' [[2-Methylthio-ATP|2-Me-SATP]]
* [[α,β-Methylene-ATP|α,β-Me-ATP]]
* [[Adenosine]]
* [[Adenosine diphosphate|ADP]]
* [[Adenosine monophosphate|AMP]]
* [[Diadenosine tetraphosphate|Ap4A]]
* [[Diadenosine pentaphosphate|Ap5A]]
* [[Adenosine triphosphate|ATP]]
* [[Adenosine-5'-(γ-thio)-triphosphate|ATPγS]]
* [[BzATP]]
* [[Cibacron blue]]
* [[Cytidine triphosphate|CTP]]
* [[D-β,γ-Me-ATP]]
* [[Guanosine triphosphate|GTP]]
* [[HT-AMP]]
* [[Ivermectin]]
* [[L-β,γ-Me-ATP]]
* [[MRS-2219]]
* [[PAPET-ATP]]
* [[Uridine triphosphate|UTP]]
* [[Zinc]]

* '''Antagonists:''' [[5-BDBD]]
* [[A-317491]]
* [[A-438079]]
* [[A-740003]]
* [[A-804598]]
* [[A-839977]]
* [[AF-353]]
* [[AZ-10606120]]
* [[AZ-11645373]]
* [[Brilliant Blue G|BBG]]
* [[Calcium]]
* [[Calmidazolium]]
* [[Chelerythrine]]
* [[Copper]]
* [[Emodin]] (''[[Rheum officinale]]'')
* [[Evans blue (dye)|Evans blue]]
* [[Gefapixant]]
* [[GW-791343]]
* [[5-(N,N-Hexamethylene)amiloride|HMA]]
* [[Diinosine pentaphosphate|Ip5I]]
* [[isoPPADS]]
* [[JNJ-47965567]]
* [[KN-04]]
* [[KN-62]]
* [[Magnesium]]
* [[MRS-2159]]
* [[NF-023]]
* [[NF-110]]
* [[NF-157]]
* [[NF-279]]
* [[NF-449]]
* [[Opiranserin|Opiranserin (VVZ-149)]]
* [[Oxidized-ATP]]
* [[Phenol Red]]
* [[Phenolphthalein]]
* [[PPADS]]
* [[PPNDS]]
* [[PSB-12062]]
* [[Puerarin]] (''[[Radix puerariae]]'')
* [[Purotoxin 1]]
* [[Reactive Blue 2|RB-2]]
* [[Ro 0437626]]
* [[Ro 51]]
* [[RO-3]]
* [[Sodium ferulate]] (''[[Angelica sinensis]]'', ''[[Ligusticum wallichii]]'')
* [[Suramin]]
* [[TC-P 262]]
* [[Tetramethylpyrazine|Tetramethylpyrazine (ligustrazine)]] (''[[Ligusticum wallichii]]'')
* [[TNP-ATP]]
* [[Zinc]]

| group2 = [[P2Y receptor|P2Y]]
| list2 =
* '''Agonists:''' [[2-Methylthioladenosine diphosphate|2-Me-SADP]]
* [[2-Methylthioadenosine triphosphate|2-Me-SATP]]
* [[2-Thio-UTP]]
* [[5-Bromouridine 5′-diphosphate|5-Br-UDP]]
* [[5-OMe-UDP]]
* [[α,β-Methylene-ATP|α,β-Me-ATP]]
* [[Adenosine]]
* [[Adenosine diphosphate|ADP]]
* [[Adenosine-5'-(β-thio)-diphosphate|ADPβS]]
* [[Diadenosine triphosphate|Ap3A]]
* [[AR-C 67085MX]]
* [[Adenosine triphosphate|ATP]]
* [[Adenosine-5'-(γ-thio)-triphosphate|ATPγS]]
* [[Cytidine triphosphate|CTP]]
* [[Deoxyadenosine triphosphate|dATP]]
* [[Denufosol]]
* [[Diquafosol]]
* [[Inosine diphosphate|IDP]]
* [[Inosine triphosphate|ITP]]
* [[INS-365]]
* [[INS-37217]]
* [[MRS-2365]]
* [[MRS-2690]]
* [[MRS-2693]]
* [[MRS-2768]]
* [[MRS-2957]]
* [[MRS-4062]]
* [[NF-546]]
* [[PAPET-ATP]]
* [[PSB-0474]]
* [[PSB-1114]]
* [[Uridine diphosphate|UDP]]
* [[Uridine 5´-(β-thio)-diphosphate|UDPβS]]
* [[Uridine diphosphate galactose|UDP-galactose]]
* [[Uridine diphosphate glucose|UDP-glucose]]
* [[Uridine diphosphate N-acetylglucosamine|UDP-N-acetylglucosamine]]
* [[Diuridine triphosphate|Up3U]]
* [[Uridine triphosphate|UTP]]
* [[Uridine-5'-(γ-thio)-triphosphate|UTPγS]]

* '''Antagonists:''' [[2-Methylthioladenosine monophosphate|2-Me-SAMP]]
* [[A3P5PS]]
* [[AMPαS]]
* [[Diadenosine tetraphosphate|Ap4A]]
* [[AR-C 66096]]
* [[AR-C 67085MX]]
* [[AR-C 69931MX]]
* [[AR-C 118925XX]]
* [[Adenosine triphosphate|ATP]]
* [[BzATP]]
* [[C1330-7]]
* [[Cangrelor]]
* [[Clopidogrel]]
* [[Elinogrel]]
* [[Diinosine pentaphosphate|Ip5I]]
* [[MRS-2179]]
* [[MRS-2211]]
* [[MRS-2279]]
* [[MRS-2395]]
* [[MRS-2500]]
* [[MRS-2578]]
* [[NF-157]]
* [[NF-340]]
* [[2,2'-Pyridylisatogen tosylate|PIT]]
* [[PPADS]]
* [[Prasugrel]]
* [[PSB-0739]]
* [[Reactive Blue 2|RB-2]]
* [[Regrelor]]
* [[Suramin]]
* [[Ticagrelor]]
* [[Ticlopidine]]
* [[Uridine diphosphate|UDP]]

}}

}}

| group2 = [[Membrane transport protein|Transporter]] ([[Reuptake inhibitor|blockers]])
| list2 = {{Navbox|child
| groupstyle = text-align:center;
| groupwidth = 6em;

| group1 = {{abbrlink|CNTs|Concentrative nucleoside transporters}}
| list1 =
* [[6-Hydroxy-7-methoxyflavone]]
* [[Adenosine]]
* [[dMeThPmR]]
* [[Estradiol]]
* [[KGO-2142]]
* [[KGO-2173]]
* [[MeThPmR]]
* [[Phloridzin]]
* [[Progesterone]]

| group2 = {{abbrlink|ENTs|Equilibrative nucleoside transporters}}
| list2 =
* [[Barbiturate]]s
* [[Benzodiazepine]]s
* [[Cilostazol]]
* [[Dilazep]]
* [[Dipyridamole]]
* [[Estradiol]]
* [[Ethanol]]
* [[Hexobendine]]
* [[6-S-((4-Nitrophenyl)methyl)-6-thioinosine|NBMPR]]
* [[Pentoxifylline]]
* [[Progesterone]]
* [[Propentofylline]]

| group3 = {{abbrlink|PMAT|Plasma membrane monoamine transporter}}
| list3 =
* [[Decynium-22]]

}}

| group3 = [[Enzyme]] ([[Enzyme inhibitor|inhibitor]]s)
| list3 = {{Navbox|child
| groupstyle = text-align:center;
| groupwidth = 6em;

| group1 = {{abbrlink|XO|Xanthine oxidase}}
| list1 =
* [[Allopurinol]]
* [[Amflutizole]]
* [[Benzbromarone]]
* [[Caffeic acid]]
* [[Cinnamaldehyde]]
* ''[[Cinnamomum osmophloeum]]''
* [[Febuxostat]]
* [[Myo-inositol]]
* [[Kaempferol]]
* [[Myricetin]]
* [[Niraxostat]]
* [[Oxipurinol]]
* [[Phytic acid]]
* ''[[Pistacia integerrima]]''
* [[Propolis]]
* [[Quercetin]]
* [[Tisopurine]]
* [[Topiroxostat]]

| group2 = Others
| list2 =
* [[Aminopterin]]
* [[Azathioprine]]
* [[Methotrexate]]
* [[Mycophenolic acid]]
* [[Pemetrexed]]
* [[Pralatrexate]]
* ''Many others''

}}

| group4 = Others
| list4 =
* '''Precursors:''' [[Adenine]]
* [[Adenosine]]
* [[Adenosine monophosphate|AMP]]
* [[Adenosine diphosphate|ADP]]
* [[Adenosine triphosphate|ATP]]
* [[Cytosine]]
* [[Cytidine]]
* [[Cytidine monophosphate|CMP]]
* [[Cytidine diphosphate|CDP]]
* [[Cytidine triphosphate|CTP]]
* [[Guanine]]
* [[Guanosine]]
* [[Guanosine monophosphate|GMP]]
* [[Guanosine diphosphate|GDP]]
* [[Guanosine triphosphate|GTP]]
* [[Hypoxanthine]]
* [[Inosine]]
* [[Inosine monophosphate|IMP]]
* [[Inosine diphosphate|IDP]]
* [[Inosine triphosphate|ITP]]
* [[Ribose]]
* [[Uracil]]
* [[Uridine]]
* [[Uridine monophosphate|UMP]]
* [[Uridine diphosphate|UDP]]
* [[Uridine triphosphate|UTP]]

* '''Others:''' [[Chrysophanol]] ([[rhubarb]])

| below = '''''See also:''' [[Template:Receptor modulators|Receptor/signaling modulators]]''

}}<noinclude>
{{collapsible option}}
[[Category:Drug templates by receptor, channel, or pump]]
</noinclude>

Template:Purine receptor modulators - Revision history