https://wiki.tiffa.net/w/index.php?action=history&feed=atom&title=Template%3AGlycine_receptor_modulators
Template:Glycine receptor modulators - Revision history
2026-08-24T03:47:05Z
Revision history for this page on the wiki
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Fire: Created page with "{{Navbox | name = Glycine receptor modulators | title = Glycine receptor modulators | bodyclass = hlist | groupstyle = text-align:center; | state = {{{state<includeonly>|collapsed</includeonly>}}} | group1 = Receptor<br /><small>(ligands)</small> | list1 = {{Navbox|subgroup | groupstyle = text-align:center; | groupwidth = 4em; | group1 = {{abbrlink|GlyR|Glycine receptor}}..."
2023-11-14T23:31:07Z
<p>Created page with "{{Navbox | name = Glycine receptor modulators | title = <a href="/w/index.php?title=Glycine_receptor&action=edit&redlink=1" class="new" title="Glycine receptor (page does not exist)">Glycine receptor</a> <a href="/w/index.php?title=Receptor_modulator&action=edit&redlink=1" class="new" title="Receptor modulator (page does not exist)">modulators</a> | bodyclass = hlist | groupstyle = text-align:center; | state = {{{state<includeonly>|collapsed</includeonly>}}} | group1 = <a href="/w/index.php?title=Receptor_(biochemistry)&action=edit&redlink=1" class="new" title="Receptor (biochemistry) (page does not exist)">Receptor</a><br /><small>(<a href="/w/index.php?title=Ligand_(biochemistry)&action=edit&redlink=1" class="new" title="Ligand (biochemistry) (page does not exist)">ligands</a>)</small> | list1 = {{Navbox|subgroup | groupstyle = text-align:center; | groupwidth = 4em; | group1 = {{abbrlink|GlyR|Glycine receptor}}..."</p>
<p><b>New page</b></p><div>{{Navbox<br />
| name = Glycine receptor modulators<br />
| title = [[Glycine receptor]] [[receptor modulator|modulator]]s<br />
| bodyclass = hlist<br />
| groupstyle = text-align:center;<br />
| state = {{{state<includeonly>|collapsed</includeonly>}}}<br />
<br />
| group1 = [[Receptor (biochemistry)|Receptor]]<br /><small>([[Ligand (biochemistry)|ligand]]s)</small><br />
| list1 = {{Navbox|subgroup<br />
| groupstyle = text-align:center;<br />
| groupwidth = 4em;<br />
<br />
| group1 = {{abbrlink|GlyR|Glycine receptor}}<br />
| list1 =<br />
* '''Agonists:''' [[β-Alanine]]<br />
* [[Beta-Aminobutyric acid|β-ABA (BABA)]]<br />
* [[β-Aminoisobutyric acid|β-AIBA]]<br />
* [[Caesium]]<br />
* [[Alanine|<small>D</small>-Alanine]]<br />
* [[Serine|<small>D</small>-Serine]]<br />
* [[gamma-Aminobutyric acid|GABA]]<!--PMID: 18304476--><br />
* [[Glycine]]<br />
* [[Hypotaurine]]<br />
* [[Ivermectin]]<br />
* [[Alanine|<small>L</small>-Alanine]]<br />
* [[Proline|<small>L</small>-Proline]]<br />
* [[Serine|<small>L</small>-Serine]]<br />
* [[Threonine|<small>L</small>-Threonine]]<!--Prodrug to glycine--><br />
* [[MDL-27531]]<br />
* [[Milacemide]]<!--Prodrug to glycine--><br />
* [[Picolinic acid]]<br />
* [[Propofol]]<!--At high concentrations--><br />
* [[Quisqualamine]]<br />
* [[Sarcosine]]<br />
* [[Taurine]]<br />
<br />
* '''Positive modulators:''' [[Alcohol (chemistry)|Alcohol]]s (e.g., [[brometone]], [[chlorobutanol|chlorobutanol (chloretone)]], [[alcohol (drug)|ethanol (alcohol)]], [[tert-Butyl alcohol|''tert''-butanol (2M2P)]], [[tribromoethanol]], [[trichloroethanol]], [[trifluoroethanol]])<br />
* [[Alkylbenzene sulfonate]]<br />
* [[Anandamide]]<br />
* [[Barbiturate]]s (e.g., [[pentobarbital]], [[sodium thiopental]])<br />
* [[Chlormethiazole]]<br />
* [[D12-116]]<br />
* [[Dihydropyridine]]s (e.g., [[nicardipine]])<br />
* [[Etomidate]]<br />
* [[Ginseng]] constituents (e.g., [[ginsenoside]]s (e.g., [[ginsenoside-Rf]]))<br />
* [[Glutamic acid|Glutamic acid (glutamate)]]<br />
* [[Ivermectin]]<br />
* [[Ketamine]]<br />
* [[Neuroactive steroid]]s (e.g., [[alfaxolone]], [[pregnenolone|pregnenolone (eltanolone)]], [[pregnenolone acetate]], [[minaxolone]], [[ORG-20599]])<br />
* [[Nitrous oxide]]<br />
* [[Penicillin G]]<br />
* [[Propofol]]<br />
* [[Tamoxifen]]<br />
* [[Tetrahydrocannabinol]]<br />
* [[Triclofos]]<br />
* [[Tropeine]]s (e.g., [[atropine]], [[bemesetron]], [[cocaine]], [[LY-278584]], [[tropisetron]], [[zatosetron]])<br />
* [[Volatility (chemistry)|Volatiles]]/[[gas]]es (e.g., [[chloral hydrate]], [[chloroform]], [[desflurane]], [[diethyl ether|diethyl ether (ether)]], [[enflurane]], [[halothane]], [[isoflurane]], [[methoxyflurane]], [[sevoflurane]], [[toluene]], [[1,1,1-trichloroethane|trichloroethane (methyl chloroform)]], [[trichloroethylene]])<br />
* [[Xenon]]<br />
* [[Zinc]]<br />
<br />
* '''Antagonists:''' [[2-Aminostrychnine]]<br />
* [[2-Nitrostrychnine]]<br />
* [[4-Phenyl-4-formyl-N-methylpiperidine]]<br />
* [[α-Ethyl-α-methyl-γ-thiobutyrolactone|αEMBTL]]<br />
* [[Bicuculline]]<br />
* [[Brucine]]<br />
* [[Cacotheline]]<br />
* [[Caffeine]]<br />
* [[Colchicine]]<br />
* [[Colubrine]]<br />
* [[Cyanotriphenylborate]]<br />
* [[Dendrobine]]<br />
* [[Diaboline]]<br />
* [[Endocannabinoid]]s (e.g., [[2-arachidonylglycerol|2-AG]], [[anandamide|anandamide (AEA)]])<br />
* [[Gaboxadol|Gaboxadol (THIP)]]<br />
* [[Gelsemine]]<br />
* [[iso-THAZ]]<br />
* [[Isobutyric acid]]<br />
* [[Isonipecotic acid]]<br />
* [[Isostrychnine]]<br />
* [[Laudanosine]]<br />
* [[N-Methylbicuculline]]<br />
* [[N-Methylstrychnine]]<br />
* [[N,N-Dimethylmuscimol]]<br />
* [[Nipecotic acid]]<br />
* [[Pitrazepin]]<br />
* [[Pseudostrychnine]]<br />
* [[Quinoline]]s (e.g., [[4-hydroxyquinoline]], [[4-hydroxyquinoline-3-carboxylic acid]], [[5,7-dichloro-4-hydroxyquinoline-3-carboxylic acid|5,7-CIQA]], [[7-chloro-4-hydroxyquinoline|7-CIQ]], [[7-trifluoromethyl-4-hydroxyquinoline|7-TFQ]], [[7-trifluoromethyl-4-hydroxyquinoline-3-carboxylic acid|7-TFQA]])<br />
* [[RU-5135]]<br />
* [[Sinomenine]]<br />
* [[Strychnine]]<br />
* [[Thiocolchicoside]]<br />
* [[Tutin (toxin)|Tutin]]<br />
<br />
* '''Negative modulators:''' [[Amiloride]]<br />
* [[Benzodiazepine]]s (e.g., [[bromazepam]], [[clonazepam]], [[diazepam]], [[flunitrazepam]], [[flurazepam]])<br />
* [[Corymine]]<br />
* [[Cyanotriphenylborate]]<br />
* [[Daidzein]]<br />
* [[Dihydropyridine]]s (e.g., [[nicardipine]], [[nifedipine]], [[nitrendipine]])<br />
* [[Furosemide]]<br />
* [[Genistein]]<br />
* [[Ginkgo biloba|Ginkgo]] constituents (e.g., [[bilobalide]], [[ginkgolide]]s (e.g., [[ginkgolide A]], [[ginkgolide B]], [[ginkgolide C]], [[ginkgolide J]], [[ginkgolide M]]))<br />
* [[Imipramine]]<br />
* [[NBQX]]<br />
* [[Neuroactive steroid]]s (e.g., [[3α-androsterone sulfate]], [[3β-androsterone sulfate]], [[11-deoxycorticosterone|deoxycorticosterone]], [[DHEA sulfate]], [[pregnenolone sulfate]], [[progesterone]])<br />
* [[Opioid]]s (e.g., [[codeine]], [[dextromethorphan]], [[dextrorphan]], [[levomethadone]], [[levorphanol]], [[morphine]], [[oripavine]], [[pethidine]], [[thebaine]])<br />
* [[Picrotoxin]] (i.e., [[picrotin]] and [[picrotoxinin]])<br />
* [[Phenylbenzene ω-phosphono-α-amino acid|PMBA]]<br />
* [[Riluzole]]<br />
* [[Tropeine]]s (e.g., [[bemesetron]], [[LY-278584]], [[tropisetron]], [[zatosetron]])<br />
* [[Verapamil]]<br />
* [[Zinc]]<br />
<br />
| group2 = {{abbrlink|NMDAR|N-Methyl-D-aspartate receptor}}<br />
| list2 =<br />
* See [[Template:Ionotropic glutamate receptor modulators|here]] instead.<br />
<br />
}}<br />
<br />
| group2 = [[Neurotransmitter transporter|Transporter]]<br /><small>([[Reuptake inhibitor|blocker]]s)</small><br />
| list2 = {{Navbox|subgroup<br />
| groupstyle = text-align:center;<br />
| groupwidth = 4em;<br />
<br />
| group1 = {{abbrlink|GlyT1|Glycine transporter 1}}<br />
| list1 = <br />
* [[ACPPB]]<br />
* [[ALX-1393]]<br />
* [[ALX-5407|ALX-5407 (NFPS)]]<br />
* [[AMG-747]]<br />
* [[ASP2535]]<br />
* [[Bitopertin|Bitopertin (RG1678/RO4917838)]]<br />
* [[CP-802079]]<br />
* [[Alcohol (drug)|Ethanol (alcohol)]]<br />
* [[Glycyldodecylamide]]<br />
* [[GSK1018921]]<br />
* [[LY-2365109]]<br />
* [[ORG-24598]]<br />
* [[ORG-25935|ORG-25935 (SCH-900435)]]<br />
* [[Pesampator|Pesampator (BIIB-104, PF-04958242)]]<br />
* [[PF-02545920]] ([[Mardepodect]])<br />
* [[PF-03463275]]<br />
* [[Sarcosine]]<br />
* [[SSR-103,800]]<br />
* [[SSR-504,734]]<br />
<br />
| group2 = {{abbrlink|GlyT2|Glycine transporter 2}}<br />
| list2 = <br />
* [[Amoxapine]]<br />
* [[Alcohol (drug)|Ethanol (alcohol)]]<br />
* [[N-Arachidonylglycine|NAGly]]<br />
* [[Opiranserin|Opiranserin (VVZ-149)]]<br />
* [[ORG-25543]]<br />
* [[VVZ-368]]<br />
<br />
<!-- | group3 = [[Vesicular inhibitory amino acid transporter|VIAAT]]<br />
| list3 = .....--><br />
<br />
}}<br />
<br />
<!-- | group3 = [[Enzyme]]<br /><small>([[Enzyme inhibitor|inhibitor]]s)</small><br />
| list3 = {{Navbox|subgroup<br />
| groupstyle = text-align:center;<br />
| groupwidth = 4em;<br />
<br />
| group1 = [[Serine hydroxymethyltransferase|SHMT]]<br />
| list1 = .....<br />
<br />
| group2 = [[Glycine decarboxylase complex|GDC]]<br />
| list2 = .....<br />
<br />
| group3 = [[D-amino acid oxidase|DAAO]]<br />
| list3 = .....<br />
<br />
}}--><br />
<br />
| below = <br />
;See also<br />
: ''[[Template:Receptor modulators|Receptor/signaling modulators]]''<br />
: ''[[Template:GABA receptor modulators|GABA receptor modulators]]''<br />
: ''[[Template:GABAA receptor positive modulators|GABA<sub>A</sub> receptor positive modulators]]''<br />
: ''[[Template:Ionotropic glutamate receptor modulators|Ionotropic glutamate receptor modulators]]''<br />
<br />
}}<noinclude><br />
{{collapsible option}}<br />
<br />
[[Category:Drug templates by receptor, channel, or pump]]<br />
<br />
</noinclude></div>
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