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2024-04-12T14:02:05Z

Marked this version for translation

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	<languages />		<languages />
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	{{Short description\|Chemical compound}}		{{Short description\|Chemical compound}}
	{{Drugbox		{{Drugbox
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	\| image = Tacalcitol.svg		\| image = Tacalcitol.svg

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	<!--Clinical data-->		<!--Clinical data-->
	\| tradename =		\| tradename =
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	\| routes_of_administration = Topical		\| routes_of_administration = Topical

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	<!--Pharmacokinetic data-->		<!--Pharmacokinetic data-->
	\| bioavailability =		\| bioavailability =
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	\| excretion =		\| excretion =

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	<!--Identifiers-->		<!--Identifiers-->
	\| CAS_number_Ref = {{cascite\|correct\|??}}		\| CAS_number_Ref = {{cascite\|correct\|??}}
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	\| ChemSpiderID = 4446823		\| ChemSpiderID = 4446823

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	<!--Chemical data-->		<!--Chemical data-->
	\| C=27 \| H=44 \| O=3		\| C=27 \| H=44 \| O=3
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	}}		}}

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	'''Tacalcitol''' (1,24-dihydroxyvitamin D<sub>3</sub>) is a synthetic [[vitamin D3\|vitamin D<sub>3</sub>]] analog. Tacalcitol is marketed under several names, including '''Curatoderm''' and '''Bonalfa'''.		'''Tacalcitol''' (1,24-dihydroxyvitamin D<sub>3</sub>) is a synthetic [[vitamin D3\|vitamin D<sub>3</sub>]] analog. Tacalcitol is marketed under several names, including '''Curatoderm''' and '''Bonalfa'''.

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	It is on the [[WHO Model List of Essential Medicines\|World Health Organization's List of Essential Medicines]].		It is on the [[WHO Model List of Essential Medicines\|World Health Organization's List of Essential Medicines]].

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	==Mechanism==		==Mechanism==
	Tacalcitol reduces excessive cell turnover in the epidermis by interacting with [[vitamin D receptor]]s on [[keratinocytes]].		Tacalcitol reduces excessive cell turnover in the epidermis by interacting with [[vitamin D receptor]]s on [[keratinocytes]].

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	==Uses==		==Uses==
	It is usually prescribed by a general practitioner or dermatologist for the treatment of [[psoriasis]], chronic [[chapped lips]] and other severe dry skin conditions because of its ability to reduce excessive skin cell turnover. It is available as an ointment or lotion.		It is usually prescribed by a general practitioner or dermatologist for the treatment of [[psoriasis]], chronic [[chapped lips]] and other severe dry skin conditions because of its ability to reduce excessive skin cell turnover. It is available as an ointment or lotion.

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	It has also been used for [[vitiligo]] and [[Hailey-Hailey disease]].		It has also been used for [[vitiligo]] and [[Hailey-Hailey disease]].

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	{{Antipsoriatics}}		{{Antipsoriatics}}
	{{Vitamin D receptor modulators}}		{{Vitamin D receptor modulators}}

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	{{二次利用\|date=11 February 2024}}		{{二次利用\|date=11 February 2024}}
	[[Category:Secosteroids]]		[[Category:Secosteroids]]

Fire: /* Uses */

2024-04-12T13:58:41Z

Uses

← Older revision		Revision as of 22:58, 12 April 2024
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	==Uses==		==Uses==
	It is usually prescribed by a general practitioner or dermatologist for the treatment of [[psoriasis]], chronic [[chapped lips]] and other severe dry skin conditions because of its ability to reduce excessive skin cell turnover.~~<ref name="pmid9257082" />~~ It is available as an ointment or lotion.		It is usually prescribed by a general practitioner or dermatologist for the treatment of [[psoriasis]], chronic [[chapped lips]] and other severe dry skin conditions because of its ability to reduce excessive skin cell turnover. It is available as an ointment or lotion.

	It has also been used for [[vitiligo]] and [[Hailey-Hailey disease]].		It has also been used for [[vitiligo]] and [[Hailey-Hailey disease]].

Fire: Created page with " {{Short description|Chemical compound}} {{Drugbox | Verifiedfields = changed | Watchedfields = changed | verifiedrevid = 376121485 | IUPAC_name = (1''S'',3''R'',5''Z'',7''E'',24''R'')-9,10-secocholesta-5,7,10-triene-1,3,24-triol | image = Tacalcitol.svg | tradename = | Drugs.com = {{drugs.com|international|tacalcitol}} | pregnancy_AU = | pregnancy_US =

Tacalcitol - Revision history

Fire: Marked this version for translation

Fire: /* Uses */