https://wiki.tiffa.net/w/index.php?action=history&feed=atom&title=Fursultiamine%2Fen Fursultiamine/en - Revision history 2026-04-20T10:00:24Z Revision history for this page on the wiki MediaWiki 1.43.0 https://wiki.tiffa.net/w/index.php?title=Fursultiamine/en&diff=133287&oldid=prev FuzzyBot: Updating to match new version of source page 2024-04-03T00:44:35Z <p>Updating to match new version of source page</p> <p><b>New page</b></p><div>&lt;languages /&gt;<br /> {{Short description|Chemical compound}}<br /> {{Drugbox<br /> | IUPAC_name = &#039;&#039;N&#039;&#039;-[(4-Amino-2-methylpyrimidin-5-yl)methyl]-&#039;&#039;N&#039;&#039;-&lt;nowiki&gt;{&lt;/nowiki&gt;(1&#039;&#039;E&#039;&#039;)-4-hydroxy-1-methyl-2-[(tetrahydrofuran-2-ylmethyl)disulfanyl]but-1-en-1-yl}formamide<br /> | image = Fursultiamine.png<br /> | alt = Skeletal formula of fursultiamine<br /> | width = 200<br /> | image2 = Fursultiamine 3D ball.png<br /> | alt2 = Ball-and-stick model of the fursultiamine molecule<br /> | width2 = 200<br /> <br /> &lt;!--Clinical data--&gt;<br /> | tradename = <br /> | Drugs.com = {{drugs.com|international|fursultiamine}}<br /> | pregnancy_category = <br /> | legal_status = otc<br /> | routes_of_administration = [[Mouth|Oral]]<br /> <br /> &lt;!--Pharmacokinetic data--&gt;<br /> | bioavailability = <br /> | metabolism = <br /> | elimination_half-life = <br /> | excretion =<br /> <br /> &lt;!--Identifiers--&gt;<br /> | CAS_number = 804-30-8<br /> | ATC_prefix = None<br /> | ATC_suffix = <br /> | PubChem = 3002119<br /> | ChEMBL = 1740659<br /> | DrugBank_Ref = {{drugbankcite|changed|drugbank}}<br /> | DrugBank = DB08966<br /> | ChemSpiderID = 2273321<br /> | UNII_Ref = {{fdacite|correct|FDA}}<br /> | UNII = 05J61265PX<br /> <br /> &lt;!--Chemical data--&gt;<br /> | C=17 | H=26 | N=4 | O=3 | S=2 <br /> | smiles = O=CN(\C(=C(\SSCC1OCCC1)CCO)C)Cc2cnc(nc2N)C<br /> }}<br /> <br /> &#039;&#039;&#039;Fursultiamine&#039;&#039;&#039; ([[International Nonproprietary Name|INN]]; chemical name &#039;&#039;&#039;thiamine tetrahydrofurfuryl disulfide&#039;&#039;&#039; or &#039;&#039;&#039;TTFD&#039;&#039;&#039;; brand names &#039;&#039;&#039;Adventan&#039;&#039;&#039;, &#039;&#039;&#039;Alinamin-F&#039;&#039;&#039;, &#039;&#039;&#039;Benlipoid&#039;&#039;&#039;, &#039;&#039;&#039;Bevitol Lipophil&#039;&#039;&#039;, &#039;&#039;&#039;Judolor&#039;&#039;&#039;, &#039;&#039;&#039;Lipothiamine&#039;&#039;&#039;) is a medication and vitamin used to treat [[thiamine]] deficiency. Chemically, it is a [[disulfide]] [[derivative (chemistry)|derivative]] of thiamine and is similar in structure to [[allithiamine]].<br /> <br /> It was synthesized in [[Japan]] in the 1960s from [[allithiamine]] for the purpose of developing forms of thiamine with improved [[lipophilicity]] for treating [[Thiamine#Deficiency|vitamin B&lt;sub&gt;1&lt;/sub&gt; deficiency]] (i.e., [[beriberi]]), It was subsequently commercialized not only in Japan but also in [[Spain]], [[Austria]], [[Germany]], and the [[United States]].<br /> <br /> == See also ==<br /> * [[Vitamin B1 analogue|Vitamin B&lt;sub&gt;1&lt;/sub&gt; analogue]]<br /> <br /> == Further reading ==<br /> * {{cite journal | vauthors = Lonsdale D | title = Thiamine tetrahydrofurfuryl disulfide: a little known therapeutic agent | journal = Medical Science Monitor | volume = 10 | issue = 9 | pages = RA199–203 | date = September 2004 | pmid = 15328496 | url = http://www.medscimonit.com/fulltxt.php?ICID=11763 }}<br /> <br /> {{Vitamins}}<br /> <br /> {{二次利用|date=6 April 2023}}<br /> [[Category:Formamides]]<br /> [[Category:Organic disulfides]]<br /> [[Category:Aminopyrimidines]]<br /> [[Category:Tetrahydrofurans]]<br /> [[Category:Prodrugs]]<br /> [[Category:Thiamine]]</div> FuzzyBot