Cytochrome P450 - Revision history

Fire: Marked this version for translation

2024-03-15T11:35:21Z

Marked this version for translation

Fire at 11:35, 15 March 2024

2024-03-15T11:35:09Z

← Older revision		Revision as of 20:35, 15 March 2024
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			<languages />
			<translate>
	{{Short description\|Class of enzymes}}		{{Short description\|Class of enzymes}}
	'''Cytochromes P450''' ('''P450s''' or '''CYPs''') are a [[Protein superfamily\|superfamily]] of [[enzyme]]s containing [[heme]] as a [[cofactor (biochemistry)\|cofactor]] that mostly, but not exclusively, function as [[monooxygenase]]s. In mammals, these proteins oxidize [[steroid]]s, [[fatty acid]]s, and [[xenobiotic]]s, and are important for the [[clearance (pharmacology)\|clearance]] of various compounds, as well as for hormone synthesis and breakdown, steroid hormone synthesis, drug metabolism, and the biosynthesis of [[secondary metabolite\|defensive compounds]], fatty acids, and hormones. CYP450 enzymes convert xenobiotics into hydrophilic derivatives, which are more readily excreted. In almost all of the transformations that they catalyze, P450's affect [[hydroxylation]].		'''Cytochromes P450''' ('''P450s''' or '''CYPs''') are a [[Protein superfamily\|superfamily]] of [[enzyme]]s containing [[heme]] as a [[cofactor (biochemistry)\|cofactor]] that mostly, but not exclusively, function as [[monooxygenase]]s. In mammals, these proteins oxidize [[steroid]]s, [[fatty acid]]s, and [[xenobiotic]]s, and are important for the [[clearance (pharmacology)\|clearance]] of various compounds, as well as for hormone synthesis and breakdown, steroid hormone synthesis, drug metabolism, and the biosynthesis of [[secondary metabolite\|defensive compounds]], fatty acids, and hormones. CYP450 enzymes convert xenobiotics into hydrophilic derivatives, which are more readily excreted. In almost all of the transformations that they catalyze, P450's affect [[hydroxylation]].
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	[[Category:Metabolism]]		[[Category:Metabolism]]
	[[Category:Integral membrane proteins]]		[[Category:Integral membrane proteins]]
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Fire at 07:09, 15 March 2024

2024-03-15T07:09:53Z

← Older revision		Revision as of 16:09, 15 March 2024
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	==InterPro subfamilies==		==InterPro subfamilies==
	~~{{Cleanup\|section\|reason=broken links; fragmented paragraph.\|date=September 2016}}~~
	[[InterPro]] subfamilies:		[[InterPro]] subfamilies:
	* Cytochrome P450, B-class {{InterPro\|IPR002397}}		* Cytochrome P450, B-class {{InterPro\|IPR002397}}
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	* [[CYP11 family]]		* [[CYP11 family]]
	* [[Cytochrome P450 engineering]]		* [[Cytochrome P450 engineering]]

	~~== References ==~~
	~~{{Reflist}}~~

	== Further reading ==		== Further reading ==

Fire: Created page with "{{Short description|Class of enzymes}} '''Cytochromes P450''' ('''P450s''' or '''CYPs''') are a superfamily of enzymes containing heme as a cofactor that mostly, but not exclusively, function as monooxygenases. In mammals, these proteins oxidize steroids, fatty acids, and xenobiotics, and are important for the clearance of various compounds, as well as for hormone syn..."

2024-03-15T07:09:14Z

Created page with "{{Short description|Class of enzymes}} '''Cytochromes P450''' ('''P450s''' or '''CYPs''') are a superfamily of enzymes containing heme as a cofactor that mostly, but not exclusively, function as monooxygenases. In mammals, these proteins oxidize steroids, fatty acids, and xenobiotics, and are important for the clearance of various compounds, as well as for hormone syn..."

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